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作者检查了26例多发性骨髓瘤(MM)患者最初治疗前后髂嵴骨活检的骨髓组织、骨髓瘤组织或脂肪组织百分率和生存时间(ST)之间的关系,推测剩留的正常骨髓组织(幼稚红细胞、粒细胞、巨核细胞)数量可能是判断ST的最重要因素。作者依据其它疾病的经验,怀疑骨髓瘤是从中心向近侧和远侧四肢骨骼离心地播散,因此增做了大转子和近侧胫骨活检作为后髂嵴活检的补充。
The authors examined the relationship between the percentage of bone marrow tissue, myeloma tissue, or adipose tissue, and survival time (ST) in the metatarsal biopsy of 26 patients with multiple myeloma (MM) before and after initial treatment, and hypothesized that the remaining normal bone marrow tissue ( The number of immature red blood cells, granulocytes, and megakaryocytes may be the most important factor in determining ST. Based on the experience of other diseases, the authors suspect that myeloma is scattered from the center to the proximal and distal extremities of the skeleton. Therefore, the greater trochanter and proximal tibia bone biopsy were added as a supplement to the posterior fistula biopsy.