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目的 观察健康人(HS)和功能性消化不良患者 (FD)的水负荷试验结果,并结合B超对近端胃容积进行实时测量,以观察B超水负荷试验在评价近端胃功能中的地位。方法 共纳入 60名健康人和 40例确诊FD患者,并按照是否存在明显的早饱症状将FD患者分为早饱组和非早饱组。所有受试者均重复进行水负荷试验,观察指标包括阈值饮水量 (TV)、饱足饮水量 (SV)、阈值近端胃容积(TPSV)和饱足近端胃容积(SPSV)。结果 HS组 2次检查的各观察指标差异无统计学意义。TV和SV分别为(449. 0±15. 5)ml和(1028. 0±47. 0)ml,TPSV和SPSV分别为(154. 0±8. 2)cm3 无统计学意义和(399. 0±27. 7)cm3。SV TV和SPSV TPSV存在显著相关性(r=0. 82, P<0. 001)。FD组 2次检查的各观察指标差异无统计学意义。TV和SV分别为 (464±132)ml和 (870±216)ml。HS组和FD组试验结果差异无统计学意义。但FD早饱组和非早饱组的SV和TV差异有统计学意义 [ (分别为 (372±77)ml比(525±126)ml和(700±120)ml比(998±180)ml, P<0. 01]。HS组和FD早饱组在SV和TV上差异亦有统计学意义(P<0. 01)。结论 水负荷试验具有良好的可重复性。健康人和FD早饱组的水负荷试验结果差异有统计学意义,提示早饱症状可能与近端胃功能紊乱有关,同时也说明B超水负荷试验在评价?
Objective To observe the water load test results of healthy people (HS) and functional dyspepsia patients (FD), and to measure the proximal gastric volume in real time with B ultrasound in order to observe the effect of B super-water load test in evaluating proximal gastric function status. Methods A total of 60 healthy people and 40 FD patients were enrolled in this study. Patients with FD were divided into two groups according to whether there were obvious symptoms of premature ejaculation. The water load test was repeated in all subjects. The observation indicators included the threshold water intake (TV), full water intake (SV), threshold proximal stomach volume (TPSV) and full proximal stomach volume (SPSV). Results There was no significant difference between the two groups in the observation of HS group. TV and SV were (449. 0 ± 15. 5) ml and (1028. 0 ± 47. 0) ml, TPSV and SPSV were (154. 0 ± 8. 2) cm3 no statistically significant (399. 0 ± 27. 7) cm3. There was a significant correlation between SV TV and SPSV TPSV (r = 0.82, P <0.001). There was no significant difference between the two groups in the observation of FD group. TV and SV were (464 ± 132) ml and (870 ± 216) ml, respectively. There was no significant difference in the test results between HS group and FD group. However, there were significant differences in SV and TV between SD group and non-SD group [(372 ± 77) ml (525 ± 126) ml and (700 ± 120) ml (998 ± 180) ml , P0.01) .However, the difference between SV group and TVS group was also statistically significant (P0.01) .Conclusion The water load test has a good repeatability.Human and FD early Saturated water load test results were statistically significant differences, suggesting that early symptoms may be related to proximal gastric dysfunction, but also shows that B-water load test in the evaluation?