卵泡刺激素的主要作用是促进和维持正常的性腺发育和生殖功能。其生理功能的发挥通过分布于性腺的特异性卵泡刺激素受体介导。近年 ,卵泡刺激素受体在卵巢中的表达倍受关注 ,并开始探讨卵巢癌细胞有无卵泡刺激素受体蛋白过度表达 ,从而为卵巢癌的基因治疗提供新的思路。现将卵泡刺激素受体的定位、分子结构及它在正常与病变卵巢中的表达与调控的相关研究进行综述 The main role of follicle stimulating hormone is to promote and maintain normal gonadal development and reproductive function. Its physiological function through the distribution of gonadal specific follicle-stimulating hormone receptor-mediated. In recent years, the expression of follicle stimulating hormone receptor in the ovary has drawn much attention and started to explore whether ovarian cancer cells have overexpression of the follicle stimulating hormone receptor protein, so as to provide a new idea for the gene therapy of ovarian cancer. Now the location, molecular structure of follicle stimulating hormone receptor and its related research in the expression and regulation of normal and diseased ovary