论文部分内容阅读
[目的]了解山东省西部地区健康儿童麻疹、风疹、流行性腮腺炎(腮腺炎)血清抗体水平。[方法]2010年11月,采集淄博、枣庄、莱芜、滨州、菏泽5市2～5岁、7～14岁健康儿童血标本,应用酶联免疫(ELISA)吸附法检测麻疹、风疹、腮腺炎IgG抗体。[结果]合计检测儿童661人,麻疹、风疹、腮腺炎抗体均阳性的415人,抗体阳性率为62.83%。麻疹、风疹、腮腺炎抗体阳性率分别为95.72%、75.82%、82.32%,GMC分别为1 086.93IU/ml、57.42IU/ml、79.79U/ml。麻疹抗体阳性率,2～5岁不同地区间麻疹抗体阳性率差异有统计学意义(P<0.05);风疹抗体阳性率,2～5岁组高于7～14岁(P<0.05),不同地区2～5岁、7～14岁儿童差异均有统计学意义(P<0.01);腮腺炎抗体阳性率,7～14岁高于2～5岁儿童(P<0.01),不同地区2～5岁、7～14岁儿童差异均有统计学意义(P<0.05)。[结论]山东省西部地区2～14岁儿童麻疹抗体水平较高。风疹、腮腺炎抗体水平较低,且地区间差别较大。
[Objective] To understand the serum levels of measles, rubella and mumps in healthy children in western part of Shandong Province. [Methods] In November 2010, blood samples of healthy children aged 2 ~ 5 years and 7 ~ 14 years from 5 cities of Zibo, Zaozhuang, Laiwu, Binzhou and Heze were collected to detect measles, rubella and mumps by enzyme-linked immunosorbent assay IgG antibody. [Results] A total of 415 children were tested positive for measles, rubella and mumps in 661 children. The positive rate of antibody was 62.83%. The positive rates of measles, rubella and mumps were 95.72%, 75.82% and 82.32% respectively, and the GMCs were respectively 1 086.93IU / ml, 57.42IU / ml and 79.79U / ml. The positive rate of measles antibody and the positive rate of measles antibody in different regions of 2 ~ 5 years old were significantly different (P <0.05). The positive rate of rubella antibody in 2 ~ 5 years old group was higher than that of 7 ~ 14 years old (P <0.05) The positive rate of mumps antibody was higher in children aged 2 ~ 5 years and 7 ~ 14 years (P <0.01), and was higher in children aged 2 ~ 5 years (P <0.01) The difference was statistically significant between 5 years old and 7 ~ 14 years old children (P <0.05). [Conclusion] The level of measles antibody in children aged 2-14 years in western Shandong is higher. Rubella, mumps antibody levels lower, and large differences between regions.