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目的 回顾性总结 116例卵巢恶性生殖细胞瘤的治疗。方法 1986年 1月至 1998年 1月 ,我院共收治卵巢恶性生殖细胞瘤 116例 ,占同期卵巢恶性肿瘤总数的 16 .6 %。其中 期 6 6例 , 期 19例 , 期 2 8例 , 期 3例。采用以手术为主 ,辅以化疗和放疗。结果 全组 5年生存 76例 ,占 6 0 .2 4% ,其中无性细胞瘤 2 9例 ,占 81.8% ,未成熟畸胎瘤 2 2例 ,占 6 4.1% ,内胚窦瘤 2 1例 ,占 5 2 .8% ,混合性生殖细胞瘤 2例 ,占 2 0 .0 %。结论 卵巢恶性生殖细胞瘤对化疗十分敏感 ,术后应辅以多疗程化疗。对年轻、病期早的患者宜做保守手术 ,保留生育功能。
Objective To retrospectively summarize the treatment of 116 cases of malignant ovarian germ cell tumor. Methods January 1986 to January 1998, our hospital received a total of 116 cases of ovarian malignant germ cell tumors, accounting for 16.6% of the total number of ovarian cancer over the same period. Sixty-six cases of which period, 19 cases, period of 28 cases, 3 cases. Used mainly to surgery, supplemented by chemotherapy and radiotherapy. Results The 5-year survival rate in all patients was 76 cases (60.2%), of which 29 were dysgerminoma, accounting for 81.8%, 21 cases were immature teratoma, accounting for 6 4.1%, 21 cases of endodermal sinus tumor , Accounting for 52.8%, mixed germ cell tumor in 2 cases, accounting for 20.0%. Conclusions Ovarian malignant germ cell tumor is very sensitive to chemotherapy and should be supplemented with multiple courses of chemotherapy after operation. For young, early stage patients should do conservative surgery to retain reproductive function.