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目的:探讨育宫颗粒冲剂合用克罗米芬治疗多囊卵巢综合征(PCOS)不孕的临床疗效。方法:按随机分组法设育宫颗粒合用克罗米芬116例为治疗组;单独使用克罗米芬为对照组,观察治疗前、治疗6个周期后和停药4个周期,患者性腺激素的变化、卵泡发育变化、排卵率和妊娠情况。结果:两组总疗效比较,对照组为76%,观察组为92.2%,具有显著性差异(P<0.01)。结论:育宫颗粒合用克罗米芬治疗多卵巢综合征不孕,较单独使用克罗米芬能显著提高卵泡发育质量以及排卵率和受孕率。
Objective: To investigate the clinical efficacy of Yugong granule granules combined with clomiphene in the treatment of infertility with polycystic ovary syndrome (PCOS). Methods: According to randomization method, 116 cases of kennel combined with clomiphene were used as the treatment group. Clomiphene alone was used as the control group to observe the change of gonadal hormone, follicle changes before and after 6 cycles of treatment and 4 cycles of withdrawal Developmental changes, ovulation rates and pregnancy status. Results: The total curative effect was 76% in the control group and 92.2% in the observation group, with significant difference (P <0.01). Conclusions: The combination of kyu Gong granules and clomiphene in the treatment of infertility with multiple ovarian syndrome, compared with clomiphene alone can significantly improve the quality of follicular development and ovulation rate and pregnancy rate.