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矽肺是危害工人健康常见而严重的职业病,多年来国内对矽肺的治疗积累了不少经验,获得了不同的效果;但是疗效显著的不多,就象在实验性矽肺中有抑制肺组织纤维化作用的克矽平,在临床应用中,也不能得到同样明显的疗效。为了适应防治矽肺工作的实际需要,要求寻找更多有效的药物。氯喹(磷酸氯化喹宁)是1946年开始治疗疟疾的有效药物,近年来又用作免疫抑制剂和治疗胶元疾病。1960年开始应用于实验性矽肺,我们于1974年试用它治疗少数住院
Silicosis is a common and serious occupational disease that endangers the health of workers. Over the years, a lot of experience has been accumulated in the treatment of silicosis in our country, and different effects have been obtained. However, the effect is not much, just as in experimental silicosis, the inhibition of lung fibrosis The role of Ke-Si-ping, in clinical applications, can not get the same obvious effect. In order to meet the practical needs of prevention and treatment of silicosis, require the search for more effective drugs. Chloroquine (quinine phosphate) is an effective drug for the treatment of malaria since 1946 and has been used as an immunosuppressant and adjuvant drug in recent years. Applied to experimental silicosis in 1960, we piloted it in 1974 to treat a minority of inpatients