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目的探讨小剂量多巴胺联合呋塞米治疗心力衰竭的临床疗效。方法选取四川友谊医院2015年2月—2016年10月收治的心力衰竭患者90例,根据治疗方案不同将患者分为对照组与治疗组,各45例。对照组患者予以呋塞米治疗,治疗组患者在对照组治疗基础上予以小剂量多巴胺治疗,两组患者均连续治疗2周。比较两组患者临床疗效、心功能指标[心率(HR)、收缩压(SBP)、舒张压(DBP)、左心室射血分数(LVEF)、B型尿钠肽(BNP)]及不良反应发生情况。结果治疗组患者临床疗效优于对照组(P<0.05)。治疗组患者HR、SBP、DBP、BNP水平低于对照组,LVEF高于对照组(P<0.05)。两组患者均未发生严重不良反应。结论小剂量多巴胺联合呋塞米治疗心力衰竭的临床疗效确切,可有效改善患者心功能,缓解水钠潴留等症状。
Objective To investigate the clinical efficacy of low-dose dopamine combined with furosemide in the treatment of heart failure. Methods 90 cases of heart failure patients who were treated in Sichuan Friendship Hospital from February 2015 to October 2016 were selected and divided into control group and treatment group according to different treatment plans, 45 cases in each group. Patients in the control group were treated with furosemide. The patients in the treatment group were treated with low-dose dopamine on the basis of the control group, and the patients in both groups were treated continuously for 2 weeks. The clinical efficacy, cardiac function (heart rate, SBP, DBP, LVEF, BNP) and adverse reactions were compared between the two groups Happening. Results The clinical efficacy of the treatment group was better than that of the control group (P <0.05). The levels of HR, SBP, DBP and BNP in the treatment group were lower than those in the control group, and the LVEF was higher in the treatment group than in the control group (P <0.05). No serious adverse reactions occurred in both groups. Conclusion Small dose of dopamine combined with furosemide in the treatment of heart failure has definite curative effect, which can effectively improve the patients’ cardiac function and relieve the symptoms such as Shuinazhuliu.