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目的探讨早发型重度子痫前期发病孕周对围生期母儿预后的影响。方法对58例早发型重度子痫前期患者进行临床回顾性分析。根据其发病孕周分成三组,即A组(<28周)、B组(28～32周)、C组(≥32周,且<34周)。比较分析各组孕妇并发症发生情况以及新生儿窒息率和围生儿病死率。结果早发型重度子痫前期三组患者并发症发生率随发病孕周延长而下降,但三组间差异无统计学意义;三组新生儿窒息率和围生儿病死率均随发病孕周延长而下降,且三组间差异均有统计学意义(P<0.05);B组期待治疗时间均明显长于A、C组(P<0.05),各组患者的分娩方式均以剖宫产为主。结论早发型重度子痫前期严重影响母儿健康,在保守治疗过程中,应严密监护母胎情况,适当延长孕周,适时终止妊娠,提高新生儿存活率。
Objective To investigate the effect of gestational age of early onset severe preeclampsia on prognosis of perinatal maternal. Methods 58 cases of early-onset severe preeclampsia were retrospectively analyzed. According to their gestational age, they were divided into three groups: group A (<28 weeks), group B (28 to 32 weeks) and group C (≥32 weeks, and <34 weeks). Comparative analysis of the incidence of complications of pregnant women in each group as well as neonatal asphyxia and perinatal mortality. Results The incidence of complications in early-onset severe preeclampsia patients decreased with the prolongation of their gestational weeks, but there was no significant difference among the three groups. The rates of neonatal asphyxia and perinatal mortality were all increased with the increase of gestational weeks (P <0.05). The expected duration of treatment in group B was significantly longer than that in group A and C (all P <0.05). The cesarean delivery was the main mode of delivery in each group . Conclusions Early onset severe preeclampsia seriously affects maternal and child health. In the course of conservative treatment, maternal fetal conditions should be closely monitored, gestational age should be extended appropriately, pregnancy should be terminated timely, and neonatal survival rate should be improved.