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本文以抗小鼠Ｌ３Ｔ４、Ｌｙｔ２单克隆抗体检测小鼠脾细胞中ＴＨ、Ｔｓ数，３Ｈ－ＴｄＲ掺入法淋巴细胞转化试验及白细胞介素２活性测定的方法，对经口接种卫氏并殖吸虫囊蚴小鼠及感染此虫并接受白细胞介素２治疗的小鼠进行了细胞免疫功能的动态观察。结果显示，感染小鼠脾细胞中ＴＨ减少、Ｔｓ增多，ＴＨ／Ｔｓ比值降低。刀豆素蛋白Ａ诱导的淋巴细胞转化受抑制。白细胞介素２诱导及活性测定中，靶细胞掺入的ｃｐｍ值降低。提示卫氏并殖吸虫的感染可使小鼠细胞免疫功能紊乱、降低。接受白细胞介素２活性水平高于感染组，接近正常对照组；提示白细胞介素２对增强感染卫氏并殖吸虫的小鼠细胞免疫功能有一定作用。
In this paper, anti-mouse L3T4, Lyt2 monoclonal antibody detection of mouse TH, Ts number, 3H-TdR incorporation of lymphocyte transformation assay and determination of interleukin 2 activity, oral inoculation Wensheng colonization Infection of metacercariae and mice infected with this parasite and receiving interleukin 2 treatment were used to observe the cellular immune function. The results showed that the infected mice spleen cells decreased TH, Ts increased, TH / Ts ratio decreased. Concanavalin A-induced lymphocyte transformation is inhibited. In IL-2 induction and activity assays, cpm values for target cells were decreased. Tip Wei Paragonimus infections can make mouse cellular immune dysfunction, reduced. The level of interleukin-2 (IL-2) activity was higher in the infected group than in the normal control group, suggesting that interleukin-2 may play a role in enhancing cellular immune function in Paragonimus westermani mice.