为了筛选疟疾根治药和预防药等组织期杀灭剂,迫切需要建立鼠疟实验模型。1976年我们从国外引进了约氏疟原虫(Plasmodium yoelii),同年便以小鼠为宿主,斯氏按蚊(Anopheles stephensi)为媒介,进行了建立鼠疟模型的研究,同时设计了一种作用于疟原虫红细胞前期的抗疟药筛选方法。 In order to screen the tissue-stage bactericidal agents such as malaria and prophylactic drugs, it is urgent to establish the experimental model of murine malaria. In 1976, Plasmodium yoelii was introduced from abroad. In the same year, mice were used as hosts and Anopheles stephensi as a medium to study the establishment of a murine malaria model. At the same time, an effect was designed Plasmodium malaria pre-erythrocytic antimalarial screening method.