论文部分内容阅读
目的探讨微炎症状态对透析患者的贫血及营养状况影响的程度。方法选择具有微炎症状态的透析患者52例,根据白细胞介素-6(IL-6)数值高低,分为A组(IL-6>100 pg/ml)、B组(IL-6<100 pg/ml),两组均给予促红素治疗,1个月后A组予洛汀新20 mg,每天1次,治疗2周,分别于研究开始时、1个月、2个月、3个月时检测A、B两组的IL-6、C-反应蛋白(CRP)、血清前白蛋白(PA)、血红蛋白(Hb)。结果研究开始时A、B两组的IL-6、CRP、PA、Hb比较差异有统计学意义(P<0.01);A组予干预治疗后,3个月末A、B组的IL-6、CRP、PA、Hb比较差异无统计学意义(P>0.05)。结论微炎症状态是导致透析患者贫血及营养不良的原因之一,纠正微炎症状态有利于贫血及营养不良症状的改善。
Objective To investigate the effect of microinflammatory state on anemia and nutritional status of dialysis patients. Methods 52 patients with microinflammatory state were divided into group A (IL-6> 100 pg / ml) and group B (IL-6 <100 pg / ml) according to the level of interleukin- / ml). Both groups were given erythropoietin treatment. After 1 month, group A was treated with Lotensin 20 mg once daily for 2 weeks. At the beginning of the study, one month, two months and three The levels of IL-6, C-reactive protein (CRP), serum prealbumin (PA) and hemoglobin (Hb) in A and B groups were detected at month. Results The levels of IL-6, CRP, PA and Hb in A and B groups at the beginning of the study were significantly different (P <0.01). After intervention in A group, the levels of IL-6, CRP, PA, Hb was no significant difference (P> 0.05). Conclusions Microinflammatory state is one of the reasons leading to anemia and malnutrition in dialysis patients. To correct micro-inflammatory state is beneficial to the improvement of anemia and malnutrition symptoms.