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目的观察主动免疫法联合地屈孕酮片治疗复发性流产的临床疗效。方法将经临床筛查确诊为封闭抗体阴性复发性流产(URSA)的患者100例分为两组,治疗组50例,采用淋巴细胞主动免疫法+地屈孕酮片治疗,并比较治疗前后封闭率的改变;对照组50例,采用传统保胎疗法(黄体酮注射液)治疗,观察两组疗效。结果治疗组妊娠成功率74%,对照组妊娠成功率52%,两组比较差异显著(P<0.05)。结论淋巴细胞主动免疫法联合地屈孕酮片治疗复发性流产成功率较高,有较可靠的应用价值。
Objective To observe the clinical efficacy of active immunization combined with dydrogesterone in the treatment of recurrent spontaneous abortion. Methods One hundred patients diagnosed as URSA by clinical screening were divided into two groups. The treatment group consisted of 50 patients. Active immunization with lymphocytes and dydrogesterone tablets were used. Rate of change; control group of 50 patients, the use of traditional tocolytic therapy (progesterone injection) treatment, the two groups were observed. Results The success rate of pregnancy in the treatment group was 74%, while that in the control group was 52%. There was significant difference between the two groups (P <0.05). Conclusion Active immunization of lymphocytes combined with dydrogesterone tablets in the treatment of recurrent abortion with a higher success rate, a more reliable value.