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为了解全身性炎症反应综合征（ＳＩＲＳ）向多器官功能不全综合征（ＭＯＤＳ）的发展过程，探索ＭＯＤＳ的防治策略，作者回顾性研究了１３７４例腹部外科急症患者的临床资料。结果显示：腹部外科急症患者入院时ＳＩＲＳ的发生率是３５．２％，其后ＭＯＤＳ发生率是６．４％，病死率是４．８％。经治疗（包括手术和保守治疗）４８小时后，仍伴有ＳＩＲＳ的病例中，约三分之一的患者（３３／１００）发展为ＭＯＤＳ。该１３７４例患者中，４０例发生ＭＯＤＳ（２．９％），死亡２７例（６７．５％）。作者认为，早期诊断ＳＩＲＳ，特别是注意分析治疗４８小时后仍伴有ＳＩＲＳ患者的原因，积极调控机体炎症反应，是改善腹部外科急症患者预后的关键。
To understand the development of MODS in patients with systemic inflammatory response syndrome (SIRS) and explore the strategy of prevention and treatment of MODS, the author retrospectively studied the clinical data of 1374 patients with abdominal surgery emergency. The results showed that the incidence of SIRS at hospital admission was 35.2%, followed by MODS at 6.4% and mortality at 4.8%. Forty-eight hours after treatment (including surgery and conservative treatment), about one third of patients (33/100) still having SIRS develop MODS. Among 1374 patients, MODS (2.9%) occurred in 40 patients and 27 patients died (67.5%). The authors believe that the early diagnosis of SIRS, in particular, pay attention to the analysis of 48 hours after treatment is still associated with SIRS patients, and actively regulate the body’s inflammatory response is to improve the prognosis of abdominal surgery emergency key.