过敏性紫癜为儿童最常见的结缔组织病,属祖国医学“葡萄疫”、“发斑”“肌衄”的范畴。目前西医尚无特效疗法。笔者在病房及门诊临床中,应用抗敏消癜汤治疗32例,疗效满意,现报告如下。1 临床资料 按1991年第4版《实用儿科学》诊断标准确诊为过敏性紫癜病人共32例,男25例,女7例。年龄2～6岁9例,7～10岁15例,10～14岁8例。病程在1周内者15例,2周内者6例,3周以上者11例。发病前有上感史者17例,药物过敏史者4例,原因不明者11例。全部病人均有典型的皮肤紫斑,多数分布于双下肢,合并关节肿痛者7例,腹痛呕吐得7例,紫癜性肾炎者6例。其中12例为曾用激素治疗无效或复发者。 Henoch-Schonlein purpura is the most common connective tissue disease in children, belonging to the category of “grapefruit epidemic” and “spotting” and “muscular dystrophy” in the motherland medicine. At present, there is no effective therapy in Western medicine. I ward and outpatient clinic, the application of anti-diarrhea soup cure 32 cases, the effect is satisfactory, are as follows. 1 Clinical data According to the 4th edition of 1991 “Practical Pediatrics” diagnostic criteria for the diagnosis of allergic purpura patients a total of 32 cases, 25 males and 7 females. 9 cases were aged from 2 to 6 years old, 15 cases were from 7 to 10 years old and 8 cases were from 10 to 14 years old. Course of disease in 1 week in 15 cases, 6 cases within 2 weeks, more than 3 weeks in 11 cases. Before the onset of a sense of the history of 17 cases, 4 cases of drug allergy history, 11 cases of unknown cause. All patients have a typical skin purple spots, most of the distribution in the lower extremities, joint swelling and pain in 7 cases, 7 cases of abdominal pain and vomiting, purpura nephritis in 6 cases. Twelve of them had been treated with hormone therapy or relapse.