人血白蛋白是治疗肝硬化合并水肿的药物之一,在临床上应用广泛。但是当肝功能衰竭患者合并水肿时是否可以使用白蛋白,许多临床医生存在疑虑,担心诱发肝性脑病。我们综述了既往文献,从肝性脑病的发病机制和白蛋白代谢等方面进行分析,认为可以在肝功能衰竭患者合并水肿时应用白蛋白,但应监测人血白蛋白内的氨浓度。 Human serum albumin is one of the drugs for treating cirrhosis and edema, and is widely used clinically. However, when patients with liver failure with edema can use albumin, many clinicians have doubts about the risk of inducing hepatic encephalopathy. We reviewed previous literature and analyzed the pathogenesis of hepatic encephalopathy and albumin metabolism. We believe that albumin may be used in the management of edema in patients with hepatic failure, but ammonia concentrations in human serum albumin should be monitored.