虽然微生物研究进入分子生物学快速发展的今天,但在鼠疫监测和实验研究中对特殊鼠疫菌株的检查,如何改进方法,提高细菌阳性检出率仍然不可轻视,它直接影响鼠疫监测的效果和研究工作的科学性。我们参照有关文献,用诱变的鼠疫菌株感染豚鼠,比较了脏器直接压迹培养和肉汤增菌两种检菌方法的效果,进一步证明肉汤增菌法细菌阳性检出率显著高于脏器直接压迹培养法。 Although the research of microorganism has entered the rapid development of molecular biology, how to improve the detection method of special plague strains in the plague surveillance and experimental research is still not to be underestimated. It directly affects the effect and research of plague surveillance Scientific work. We refer to the relevant literature, the use of mutagenic Yersinia pestis infected guinea pigs, comparisons of direct gravitation culture and broth enrichment of two antibacterial effect, further evidence of broth by bacteria positive detection rate was significantly higher Organ directly pressure trace culture method.