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目的了解高原地区2,4,6-三硝基甲苯(TNT)作业工人的健康状况,为高原环境因素与TNT交互作用的研究提供基础数据。方法选择海拔2300m地区某硝铵炸药厂接触TNT的生产工人184名为接触组,另选同厂不接触TNT的生产工人127名为对照组,分别对工人进行包括血常规等项目的职业健康检查,并对工厂进行职业卫生学调查。结果2000—2005年被调查的工厂工作场所空气质量TNT浓度均值均未超过国家卫生标准;接触组血红蛋白低下检出率高于对照组,有统计学意义(P<0.05),接触组白细胞和血小板降低检出率显著高于对照组(P<0.01);心电图异常检出率无统计学意义(P>0.05)。结论高原地区长期接触低浓度TNT可对作业工人产生慢性职业病危害。
Objective To understand the health status of 2,4,6-trinitrotoluene (TNT) workers in the plateau and provide basic data for the interaction between plateau environmental factors and TNT. Methods A total of 184 production workers exposed to TNT at an altitude of 2300 m in the area were exposed as TNT and 127 production workers without TNT were selected as control group to carry out occupational health checkup on workers, , And the factory for occupational hygiene survey. Results The mean concentrations of TNT in the workplace air quality surveyed in 2000-2005 did not exceed the national health standards. The detection rate of hemoglobin in the exposure group was higher than that in the control group (P <0.05). The contact white blood cells and platelets The detection rate of ECG was significantly higher than that of the control group (P <0.01). The detection rate of ECG abnormality was not statistically significant (P> 0.05). Conclusion Long-term exposure to low concentrations of TNT in the plateau may cause chronic occupational hazards to workers.