1引言谷氨酸是大脑中的主要兴奋性神经递质,是脑内神经元生长发育、成熟修复和神经传递过程中重要的神经递质。有实验表明脑脊液和血浆中谷氨酸浓度呈显著正相关(r=0.79,P0.0001),因此,测定脑脊液或血浆中谷氨酸可早期预测脑梗塞的发生。目前,测定谷氨酸的方法主要有高效液相 1 Introduction Glutamate is the major excitatory neurotransmitter in the brain and is an important neurotransmitter in the process of neuronal growth, maturation and neurotransmission in the brain. Experiments show that cerebrospinal fluid and plasma glutamate concentration was significantly correlated (r = 0.79, P0.0001), therefore, the determination of cerebrospinal fluid or plasma glutamate can be an early prediction of cerebral infarction. At present, the method of determining glutamic acid is mainly high-performance liquid phase