Ｎ乙酰半胱氨酸（ＮＡＣ）作为一种巯基化合物因其具有明显的抗氧激活性而成为化学预防研究的对象。本实验室在Ａｍｅｓ试验中证实了ＮＡＣ的抗诱变活性［１］，美国国立癌症研究所化学预防部已将ＮＡＣ进入Ｉ期临床试验［２］。近年来肺癌趋于高发，为了探讨ＮＡＣ对肺肿瘤 N-acetylcysteine ​​(NAC), as a sulfhydryl compound, has become a target of chemopreventive research due to its obvious anti-oxidative activity. Our laboratory confirmed the anti-mutagenic activity of NAC in the Ames trial [1]. The National Cancer Institute’s Department of Chemical Preventive Medicine (NAC) has entered Phase I clinical trials [2]. In recent years, lung cancer tends to be high, in order to explore the NAC on lung tumors