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目的探讨DKA患者水盐代谢异常与病情的相关性及治疗中的注意事项。方法将262例受试者根据血钠水平分为高钠(G1)组43例(Na>145mmol/L)、正常血钠(G2)组109例(135mmol/L≤Na≤145mmol/L)、轻度低钠(G3)组86例(125mmol/L≤Na<135mmol/L)及显著低钠(G4)组24例(Na<125mmol/L),评估不同血钠水平下的临床及实验室资料。结果血钠与意识障碍、BUN/Cr、有效渗透压、HCO3―存在相关性(r分别为0.341、0.123、0.853、0.196,P<0.05或P<0.01)。结论在DKA患者中常见水盐代谢异常,应注意监测,及时纠正。
Objective To investigate the correlation between abnormal water and salt metabolism and the condition in DKA patients and the precautions in the treatment. Methods According to the level of serum sodium, 262 subjects were divided into 43 cases (Na> 145mmol / L) and 109 cases (135mmol / L≤Na≤145mmol / L) Eighty-six patients (125 mmol / L≤Na <135mmol / L) and 24 patients with low (G <4mmol / L) sodium in mild hyponatremia group data. Results Serum sodium was associated with disturbance of consciousness, BUN / Cr, effective osmotic pressure and HCO3- (r = 0.341,0.123,0.853,0.196, P <0.05 or P <0.01, respectively). Conclusion Common abnormal water and salt metabolism in DKA patients should be monitored and corrected promptly.