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药物耐药是肿瘤化疗成功的最大障碍。研究表明，肿瘤细胞耐受药物的生物学基础是细胞内ｍｄｒ－１基因的过度表达。本文报告我院检测１０７例肿瘤组织ｍｄｒ－１的结果。１材料和方法１．１临床资料１０７例肿瘤组织皆为手术切取的新鲜标本。其中，胃癌２６例，大肠癌２６...
Drug resistance is the biggest obstacle to the success of cancer chemotherapy. Studies have shown that the biological basis of tumor cell tolerant drugs is the overexpression of intracellular mdr-1 gene. This article reports the results of mdr-1 detection in 107 patients with tumors in our hospital. 1 Materials and Methods 1.1 Clinical data 107 cases of tumor tissue were fresh specimens taken surgically. Among them, 26 cases of gastric cancer, 26 large intestine cancer...