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目的探讨埃索美拉唑与奥美拉唑治疗反流性食管炎的临床效果。方法 44例反流性食管炎患者作为研究对象,随机分为研究组与对照组,每组22例。研究组患者给予埃索美拉唑治疗,对照组给予奥美拉唑治疗。对两组患者的治疗效果对比分析。结果两组患者治疗后临床症状积分低于治疗前(P<0.05),且研究组患者临床症状积分低于对照组,差异具有统计学意义(P<0.05)。研究组治疗总有效率为95.5%,对照组治疗总有效率为68.2%,两组对比差异具有统计学意义(P<0.05)。两组患者不良反应对比差异无统计学意义(P>0.05)。结论临床中应用埃索美拉唑治疗反流性食管炎效果显著,值得推荐与应用。
Objective To investigate the clinical effects of esomeprazole and omeprazole in the treatment of reflux esophagitis. Methods Forty-four patients with reflux esophagitis were randomly divided into study group and control group, with 22 cases in each group. The study group was given esomeprazole and the control group was given omeprazole. The comparative analysis of the curative effect of two groups of patients. Results The score of clinical symptom in both groups after treatment was lower than that before treatment (P <0.05), and the score of clinical symptom in study group was lower than that in control group (P <0.05). The total effective rate of the study group was 95.5%, while that of the control group was 68.2%. The difference between the two groups was statistically significant (P <0.05). There was no significant difference in adverse reactions between the two groups (P> 0.05). Conclusion The clinical application of esomeprazole treatment of reflux esophagitis significant effect, it is recommended and application.