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目的探讨胃多原发癌的临床病理特征,探讨其合理的诊治方案。方法回顾性分析经病理证实的37例胃多原发癌的临床病理特征及其诊治情况,并结合文献进行分析和探讨。结果37例胃多原发恶性癌占同期收治原发胃恶性肿瘤的0.87%,其中同时多原发胃恶性肿瘤21例,异时多原发胃恶性肿瘤16例。癌灶部位以胃窦和贲门为多,病理类型以高或中分化腺癌多见。同时性胃多原发癌和异时性胃多原发癌的5年生存率分别为42.8%和52.9%。结论提高对多原发胃恶性肿瘤的诊断率主要依靠术前全面检查,术中仔细探查及术后的密切随访。早期诊断胃多原发癌并积极的手术治疗,可以提高生存率。
Objective To investigate the clinicopathological features of multiple primary gastric cancer and to explore its reasonable diagnosis and treatment. Methods The clinicopathological features, diagnosis and treatment of 37 cases of multi-primary gastric cancer confirmed by pathology were retrospectively analyzed and analyzed with literature. Results 37 cases of gastric primary malignant tumors accounted for 0.87% of primary gastric malignancies in the same period, of which 21 cases were simultaneously with primary gastric malignancies and 16 cases were heterogenous multiple primary gastric malignancies. Carcinoma site to gastric antrum and cardia as more pathological types of high or moderately differentiated adenocarcinoma more common. The 5-year survival rates of patients with multiple primary gastric cancer and simultaneous multiple gastric cancer were 42.8% and 52.9%, respectively. Conclusion The diagnosis of multiple primary gastric malignancies is mainly based on comprehensive preoperative examination, intraoperative exploration and close follow-up. Early diagnosis of multiple primary gastric cancer and aggressive surgical treatment, can improve the survival rate.