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硝苯地平(Nifedipine)片剂见效较慢,但在降低严重妊高症病人的血压方面与胶囊同样有效。已经有些研究考查了硝苯地平胶囊治疗严重妊高症的功效和安全性。相反,几乎没有研究对硝苯地平缓释片剂的疗效进行过评价。 澳大利亚悉尼市St.George医院的Dr.Mark A.Brown等人对64名严重妊高症病人的治疗结果进行了评估。这64名孕妇的血压均≥170/110 mmHg,她们随机接受10mg硝苯地平片剂或胶囊治疗。
Nifedipine tablets are less effective but are as effective as capsules in reducing blood pressure in patients with severe pregnancy-induced hypertension. Several studies have examined the efficacy and safety of nifedipine capsules in the treatment of severe pregnancy-induced hypertension. In contrast, few studies have evaluated the efficacy of nifedipine sustained-release tablets. Dr. Mark A. Brown and others at St. George’s Hospital in Sydney, Australia, evaluated the outcomes of 64 patients with severe pregnancy-induced hypertension. The 64 pregnant women had blood pressure ≥170 / 110 mmHg and they were randomized to receive 10 mg of nifedipine tablets or capsules.