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目的探讨留置胃管反复洗胃联合口服氯磷定救治急性有机磷农药中毒(AOPP)的疗效。方法将174例重度AOPP分为A、B、C三组.A组予常规一次洗胃.早期足量氯磷定、阿托品、对症及支持等综合治疗。B组在A组治疗的基础上留置胃管反复洗胃。C组在B组在治疗上再予口服氯磷定。结果A、B、C组中间综合征发生率、治愈率、病死率、病程差异均有统计学意义(P<0.05或P<0.01)。结论留置胃管反复洗胃联合口服氯磷定是救治急性有机磷农药中毒的有效方法.并能降低病死率,缩短病程,减少医疗费用。
Objective To investigate the curative effect of gastric lavage with repeated gastric lavage combined with oral chlorophosphatidylcholine in the treatment of acute organophosphorus pesticide poisoning (AOPP). Methods 174 cases of severe AOPP were divided into three groups: A, B and C. A group was treated with conventional gastric lavage once a day, early chlordecone, atropine, symptomatic and supportive treatment. B group in group A treatment based on gastric lavage repeatedly lavage. Group C was treated with oral chlorophosphonates again in group B. Results The incidence of intermediate syndrome, cure rate, case fatality rate and course of disease among groups A, B and C were all statistically significant (P <0.05 or P <0.01). Conclusion Indwelling gastric tube with repeated gastric lavage combined with oral chlorpromazine is an effective method for the treatment of acute organophosphorus pesticide poisoning, and can reduce mortality, shorten the course of disease and reduce medical costs.