遗传性心律失常的首发症状常为心源性猝死(SCD)。遗传性心律失常的特点为携带影响心脏离子电流的遗传性突变,通过基因型-表型分析发现不同突变类型的致死性心律失常,可分别在运动、情绪激动时,或睡眠、休息时发生。因此,应根据具体突变类型进行危险分层和临床治疗。近年来一些新方案的提出使遗传性心律失常的药物治疗发生了改变,这些改变在既往的指南中均未涉及。目前遗传性心律失常的国际专家共识已经制定,但临床医师 The first symptom of hereditary arrhythmia is often sudden cardiac death (SCD). Hereditary arrhythmias are characterized by inherited mutations that affect cardiac ion currents. Genotypic-phenotypic analysis revealed that fatal arrhythmias of different types of mutations can occur during exercise, emotional activity, or sleep, rest, respectively. Therefore, risk stratification and clinical treatment should be based on the type of mutation. In recent years, some new schemes have been proposed to change the medication for hereditary arrhythmia, and none of these changes have been covered in the previous guidelines. International expert consensus on current genetic arrhythmias has been developed, but clinicians