Notch与核因子κB(NF-κB)的经典信号传导途径已有较充分的研究。然而,与非经典途径及各自与其他信号途径的串话关系相比,经典途径显得比较简单。Notch信号途径与其他信号途径的串话关系较为复杂,且Notch与某些信号通路的相互作用,其生理相关性仍需得到进一步研究证实。近年来, The classical signaling pathways of Notch and NF-κB have been well studied. However, the classic approach is simpler than non-classical approaches and their crosstalk relationship with other signaling pathways. The crosstalk relationship between Notch signaling pathway and other signaling pathways is complex, and the physiological relationship between Notch and certain signaling pathways needs to be further studied. In recent years,