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目的：分析系统性红斑狼疮 (SLE)患者的死因，降低其病死率。方法：对 222例 SLE患者中的 42例死者病因进行回顾性分析。结果：主要死因是 SLE本身 19例 (45.24％ )，其次是继发感染 13例 (30.95％ )。 SLE与感染致死较常发生于年青患者。 SLE死亡多发生在诊断后的头三年。结论： SLE死亡最主要原因是 SLE本身，故对 SLE患者做到早期诊断，合理治疗，对狼疮活动者更应积极治疗，以便提高患者长期存活率，降低死亡率。
Objective: To analyze the cause of death and reduce the mortality of patients with systemic lupus erythematosus (SLE). Methods: The etiology of 42 dead cases in 222 SLE patients was retrospectively analyzed. Results: The main causes of death were SLE itself, 19 cases (45.24%), followed by secondary infection in 13 cases (30.95%). SLE and infection often occur in young patients. SLE deaths occur more frequently in the first three years after diagnosis. Conclusion: The main reason of SLE death is SLE itself. Therefore, early diagnosis and reasonable treatment of patients with SLE should be made and more active treatment should be given to lupus active patients in order to improve the long-term survival rate and reduce the mortality rate.