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本文总结我院自1973—1978年间,住院治疗的何杰金氏病51例的临床表现及治疗结果。平均年龄31岁,31—50岁为就诊时的高峰年龄。男性发病率高于女性。病理类型以混合细胞型为最多见(28.8%),淋巴细胞为主型次之(21.7%)与苏州医学院所报道之资料相近似。临床表现多以无痛性淋巴结肿大为首发症状(88%),伴有全身症状者为33%。本组近期有效率为86.9%,中数缓解期为4个月。一年存活率为74.1%,二年50%,三年36.1%,四年27%。治疗取得完全缓解的病人3年存活率为66%,4年为50%;部分缓解的病人4年存活率为14%;治疗无效的病人85.7%,于一年内死亡。
This article summarizes the clinical manifestations and treatment outcomes of hospitalized Hodgkin’s disease in our hospital from 1973 to 1978. The average age is 31 years old, 31-50 years old is the peak age at the time of treatment. The incidence of men is higher than women. The most common histopathologic type was mixed cell type (28.8%), and lymphocyte dominant type (21.7%) was similar to the data reported by Suzhou Medical College. The most common clinical manifestations were painless lymphadenopathy as the first symptom (88%) and systemic symptoms as 33%. The current effective rate in this group was 86.9%, and the median remission period was 4 months. The one-year survival rate is 74.1%, 50% in two years, 36.1% in three years, and 27% in four years. The three-year survival rate was 66% for patients who achieved complete remission, and 50% for four years. The 4-year survival rate for partially remission patients was 14%, and 85.7% for patients who did not respond to treatment died within one year.