青少年抑郁障碍患者心理理论能力与自杀未遂的相关性研究

来源 :中华行为医学与脑科学杂志 | 被引量 : 0次 | 上传用户:rdx200901as
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目的:探讨伴与不伴自杀未遂青少年抑郁障碍患者心理理论的差异及其与抑郁严重程度的相关性。方法:2019年9月至2021年4月,纳入56例自杀未遂青少年抑郁障碍患者(自杀未遂组)、78例非自杀未遂青少年抑郁障碍患者(非自杀未遂组)以及23名性别、年龄和受教育年限相匹配的健康对照者(健康对照组),采用17项汉密尔顿抑郁量表(17-item Hamilton depression scale,HAMD-17)、国际神经精神科简式访谈问卷版本6.0.0中文版(mini-international neuropsychiatric interview,M.I.N.I.)对所有被试进行抑郁严重程度和自杀特质相关临床心理量表评定,心理理论故事图片任务(theory of mind-picture sequencing task,ToM-PST)包括初级信念、初级错误信念、次级信念、次级错误信念、三级错误信念、现实感、理解互惠、理解欺骗和欺骗侦测指标,用于测试三组被试的心理理论水平。采用SPSS 25.0对数据进行统计分析,单因素方差分析比较3组被试心理理论水平的差异,采用Pearson相关分析对自杀未遂组的心理理论水平与临床行为量表之间进行相关分析。结果:自杀未遂组在理解初级错误信念[(2.46±0.63)分]显著低于健康对照组[(2.87±0.46)分](n P<0.05),在理解欺骗问题[(2.84±0.42)分]显著高于非自杀未遂组[(2.63±0.61)分](n P<0.05),非自杀未遂组在理解初级错误信念[(2.48±0.72)分]、心理理论总分[(50.86±6.60)分]显著低于健康对照组[(2.87±0.46)分,(54.91±5.12)分](均n P<0.05)。Pearson相关分析显示,自杀未遂组的次级错误信念与HAMD17因子认知障碍呈显著负相关(n r=-0.267,n P<0.05),三级错误信念与HAMD17因子认知障碍、阻滞以及总分呈显著负相关(n r=-0.331,n r=-0.319,n r=-0.269,均n P0. 05)。n 结论:伴与不伴自杀未遂的青少年抑郁障碍患者理解欺骗的能力存在差异,差异因子分与抑郁严重程度无相关性。“,”Objective:To explore the difference of theory of mind between adolescent depressive disorder patients with and without suicide attempt and its correlation with depression severity.Methods:From September 2019 to April 2021, totally 56 cases of attempted suicide adolescent depression patients(suicide attempted group), and 78 non-attempted suicide adolescent depression patients (non-suicide attempted group) and 23 healthy controls (healthy control group) with matched sex, age and years of education were included.The 17-item Hamilton depression scale(HAMD-17) and mini-international neuropsychiatric interview (M. I. N. I. ) were evaluated in all the subjects for depression severity and suicide trait related clinical psychological scale, theory of mind-picture sequencing task (ToM-PST) includes primary belief, primary false belief, secondary belief, secondary false belief, third-level false belief, sense of reality, reciprocity, deception and deception detection, which were used to test the theory of mind of the three groups. SPSS 25.0 software was used to statistically analyze the data, compare the differences of ToM of the three groups, and Pearson correlation analysis was used to analyze the correlation between ToM of the attempted suicide group and the clinical behavior scale.Results:The suicide attempted group was significantly lower in understanding primary false belief ((2.46±0.63) n vs (2.87±0.46)) than the healthy control group(n P<0.05), and the understanding of deception((2.84±0.42)n vs (2.63±0.61)) was significantly higher than the non-suicide attempted group(n P<0.05), and the non-suicide attempted group was significantly lower in understanding primary false belief((2.48±0.72)n vs ( 2.87±0.46)) and ToM total scores((50.86±6.60) n vs (54.91±5.12)) than the healthy control group(both n P<0.05). Pearson correlation analysis showed that the secondary false belief of the attempted suicide group were negatively correlated with the cognitive impairment(n r=-0.267, n P<0.05), and third-level false belief was negatively correlated with the cognitive impairment, retardation, and depressiontotal score(n r=-0.331, n r=-0.319, n r=-0.269, all n P0.05).n Conclusion:The ability to understand deception is different between depression adolescents with and without suicide attempt, and it is not correlated with the severity of depression.
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