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目的探讨胰腺实性假乳头状瘤(SPT)的特点、外科治疗的方法及效果。方法回顾性分析1999年1月至2005年7月间14例胰腺实性假乳头状瘤的临床病理资料。结果本组患者中男性1例,女性13例。14例肿瘤均为单发,9例位于胰头,4例位于胰体,1例位于胰尾。肿瘤直径平均7.2 cm。无特异性临床表现。CT平扫:肿瘤囊性、实质部分均为低密度影,边界清楚,可见钙化; 增强后:肿瘤实质轻度强化,囊性结构动、静脉期均无强化。14例患者均行手术治疗,8例行肿瘤局部切除,2例行胰体部分切除加胰肠吻合术,1例行胰体尾加脾切除术,3例行Whipple手术。随访2- 58个月,平均随访20.1个月,所有患者均存活,无复发、转移。结论胰腺实性假乳头状瘤是一种低度恶性的肿瘤;手术切除是有效的治疗方法,术式选择与肿瘤位置、大小等因素相关;完整切除者预后良好。
Objective To investigate the characteristics of solid pseudopapillary tumor (SPT) in pancreas and the surgical treatment methods and results. Methods The clinical data of 14 patients with solid pseudopapillary pancreatic tumors from January 1999 to July 2005 were analyzed retrospectively. Results In this group, there were 1 males and 13 females. All 14 tumors were single, 9 in the pancreas, 4 in the pancreas, and 1 in the pancreas. Tumor diameter averaged 7.2 cm. No specific clinical manifestations. CT scan: cystic tumor, the real part of the low-density shadow, the border is clear, visible calcification; enhanced: the tumor slightly enhanced, cystic structure of the dynamic, no enhancement of the venous phase. All 14 patients underwent surgical resection. Eight patients underwent partial tumor resection. Two patients underwent partial pancreatic excision plus pancreaticojejunostomy. One patient underwent pancreatic body tail plus splenectomy and three patients underwent Whipple operation. All the patients were followed up for 2-58 months with an average follow-up of 20.1 months. All patients survived without recurrence and metastasis. Conclusions Solid pseudopapillary pancreatic tumor is a kind of low malignant tumor. Surgical resection is an effective treatment method. The choice of surgical procedure is related to tumor location, size and other factors. The prognosis of complete resection is good.