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许多研究结果证实,单一血清AFP在原发性肝癌中阴性率达30%以上。因此,AFP以外的多项标志物组合检测,已成为提高原发性肝癌灵敏度与特异度的重要手段。我们通过对肝癌,非肝癌及良性占位病变患者进行多项检测分析,并对其联合运用的诊断效能作出初步评价。1 材料与方法1．1 检测对象69例原发性肝癌,10例继发性肝癌,28例肝硬化,11例肝囊肿及血管瘤。全部病例均为我院近年来住院患者。经B超、CT、肝动脉造影,部分经病理活检为确诊依据。
Many studies have confirmed that the single serum AFP has a negative rate of more than 30% in primary liver cancer. Therefore, detection of multiple marker combinations other than AFP has become an important means to increase the sensitivity and specificity of primary liver cancer. We performed multiple tests and analysis on patients with hepatocellular carcinoma, non-hepatocellular carcinoma, and benign space-occupying lesions, and made a preliminary assessment of their combined use of diagnostic efficacy. 1 Materials and methods 1.1 Detection of 69 cases of primary liver cancer, 10 cases of secondary liver cancer, 28 cases of cirrhosis, 11 cases of hepatic cysts and hemangiomas. All cases were hospitalized patients in our hospital in recent years. After B-ultrasonography, CT, hepatic arteriography, some of the pathological biopsy is the basis for the diagnosis.