本文研究了维生素K_3(Vit K_3,上海大众制药厂产品)对豚鼠、大鼠和小鼠胃肠推进运动的影响。 豚鼠随机分为5组,每组8只,分别sc NS或Vit K_3(10,20,40,80mg/kg),10min后、ig5％炭末、10％阿拉伯胶悬液(2ml/只),再隔40min处死豚鼠,剖腹测定胃喷门到回盲部距离和贲门到炭末前沿距离,求炭末移动率,再以NS组为对照求抑制率。结果表明,Vit K_3剂量依赖性地抑制豚鼠胃肠推进运动,Vit K_3 In this paper, the effects of vitamin K_3 (Vit K_3, Shanghai Volkswagen Pharmaceutical Factory) on gastrointestinal motility in guinea pig, rat and mouse were studied. Guinea pigs were randomly divided into 5 groups with 8 rats in each group, sc NS or Vit K_3 (10, 20, 40 and 80 mg / kg) respectively. After 10 minutes, 5% charcoal powder and 10% Guinea pigs were sacrificed 40 minutes later, and the distance between the stomach spray and the ileocecal part and the distance between the cardia and the front of the charcoal were measured by cesarean section. The results showed that Vit K_3 dose-dependently inhibited the gastrointestinal motility in guinea pigs, Vit K_3