背景与目的光动力学疗法(PDT)对原位、非侵入性表浅肿瘤的治疗具有广阔的应用前景。光动力学疗法具有双重选择性,除光敏剂外,还需要光和氧的同时参与。对肿瘤的损伤机制主要有两类:直接损伤肿瘤细胞,导致细胞的凋亡和坏死;间接损伤肿瘤,引起微血管的封闭和其他非特异性免疫反应 Background and Objective Photodynamic therapy (PDT) has broad application prospects for the treatment of in situ and non-invasive superficial tumors. Photodynamic therapy with dual selectivity, in addition to the photosensitizer, but also the need for light and oxygen at the same time involved. There are two main types of tumor damage mechanisms: direct damage to tumor cells leading to apoptosis and necrosis of the cells; indirect damage to the tumor causing closure of the microvessels and other nonspecific immune responses