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目的观察盐酸米诺环素软膏(派丽奥)联合布洛芬对慢性牙周炎(CP)的临床疗效。方法选取医院2015年1~11月收治的CP患者86例,按照入院顺序奇偶法随机分为对照组和试验组各43例。对照组应用派丽奥治疗,试验组应用派丽奥联合布洛芬治疗;治疗2周后,比较2组出血指数、菌斑指数、附着丧失、牙周探诊深度以及总有效率。结果治疗2周后,试验组总有效率达100.00%显著高于对照组86.05%(P<0.05);试验组出血指数、菌斑指数、附着丧失、牙周探诊深度等指标均显著优于对照组,差异均有统计学意义(P<0.05)。结论与应用派力奥单药相比,联合应用派丽奥联合布洛芬治疗CP的临床疗效更佳,值得推广及应用。
Objective To observe the clinical efficacy of minocycline hydrochloride ointment combined with ibuprofen on chronic periodontitis. Methods Eighty-six CP patients admitted from January 2015 to January 2015 in our hospital were randomly divided into control group and experimental group according to the order of admission parity method. The control group was treated with Palio, and the experimental group was treated with Palio plus ibuprofen. After 2 weeks of treatment, bleeding index, plaque index, loss of attachment, depth of probing and total effective rate were compared. Results After 2 weeks of treatment, the total effective rate in the experimental group was 100.00%, which was significantly higher than that in the control group (86.05%, P <0.05). Bleeding index, plaque index, loss of attachment, depth of periodontal exploration were significantly better than those in the control group Control group, the difference was statistically significant (P <0.05). Conclusion Compared with the application of Palio alone, the combination of Palio and Ibuprofen in the treatment of CP is more effective and worthy of promotion and application.