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“胃炎平”系武汉市职工医学院附属医院中医科研制的新型中成药,本试验用其纯原料药(粉剂)对小白鼠进行了急性毒性的观察,以期确定该药被人服用是否安全、无毒。 1 试验方法 试验一,采用孙氏改良冠氏综合法,首先用10倍稀释的4种浓度的药液进行预试,以期找出0％(D_n)及100％(D_n)估计致死量。因该药是没有提纯的中药复方制剂,溶解度较小,能配成药物液状态的最大浓度为25％(超过25％即为无流动的半固体状态),故我们预试的四种药物
“Weiyanping” is a new type of proprietary Chinese medicine made by the Chinese medicine scientific research institute of the Affiliated Hospital of Wuhan Medical College of Staff and Workers. This experiment used its pure drug substance (powder) to observe the acute toxicity of mice to determine whether the drug was taken safely or not. Non-toxic. 1 Test method Test 1, using Sun’s modified Guan’s comprehensive method, first with 10 concentrations of 4 concentrations of the drug solution for a pre-test, in order to find out 0% (D_n) and 100% (D_n) estimated lethal dose. Because the drug is not a purified Chinese medicine compound preparation, the solubility is small, and the maximum concentration of the drug liquid state can be set to 25% (more than 25% is the semi-solid state without flowing), so we pre-tested four drugs