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同步检测92例肝病患者血清人Ⅲ型前胶原(HPCⅢ)和透明质酸(HA)含量。结果表明,慢性迁延性肝炎患者血清 HPCⅢ与对照组比较无显著差异;急性肝炎、原发性肝癌(单纯型)患者血清 HPCⅢ轻度升高;慢性活动性肝炎明显升高;肝硬化显著升高。各型肝病患者血清 HA 均有升高,以肝硬化升高幅度最大。本文提示同步检测血清 HPCⅢ、AH 可提高早期肝硬化的诊断率。
The levels of serum human type Ⅲ procollagen (HPC Ⅲ) and hyaluronic acid (HA) in 92 patients with liver disease were simultaneously detected. The results showed that there was no significant difference between the serum HPC Ⅲ and the control group in patients with chronic persistent hepatitis; the levels of serum HPC Ⅲ increased slightly in patients with acute hepatitis and primary liver cancer (simple type); the serum levels of chronic active hepatitis increased significantly; . Patients with various types of liver disease serum HA increased, the highest increase in cirrhosis. This paper suggests that synchronous detection of serum HPC Ⅲ, AH can improve the diagnosis of early cirrhosis.