血管紧张素转换酶(Angiotensin Converting Enzyme,ACE)抑制剂是近年用来治疗各类高血压的一类新药。该类药通过抑制肾素-血管紧张素-醛固酮系统而发挥其药理作用。目前临床应用较多的是甲巯丙脯酸(Captopril,CP)和苯酯丙脯酸(Enalapril,EP)。在ACE抑制剂应用初期,用量较大(600～12000mg/日),副作用发生较多。近年推荐应用较小剂量 Angiotensin Converting Enzyme (ACE) inhibitor is a kind of new drug used to treat all kinds of hypertension in recent years. The drug exerts its pharmacological effects by inhibiting the renin-angiotensin-aldosterone system. At present, Captopril (CP) and Enalapril (EP) are the most commonly used clinically. ACE inhibitors in the initial application, a larger amount (600 ~ 12000mg / day), side effects occur more. In recent years recommended the use of smaller doses