动物或人的肿瘤细胞中常出现个体发育阶段胚胎细胞所具有的某些蛋白质、酶、转移核糖核酸等,这已为大家所熟知(Fishman和Sell,1976)。我们曾用免疫膜荧光法对离体培养的人体肝癌细胞进行了研究,发现肝癌细胞具有与胎儿肝细胞有交叉反应的膜抗原(施渭康等,1977)。为了进一步弄清这一胚胎抗原在这些细胞表面的分布,我们用铁蛋白标记抗体技术进行了电镜观察。本实验结果进一步证实了免疫膜荧光法所观察到的现象,说明人体 It is well-known that certain proteins, enzymes, and metastases of embryonic cells in an individual’s developmental stage are often found in animal or human tumor cells (Fishman and Sell, 1976). We used immunofluorescence to study cultured human hepatoma cells in vitro and found that liver cancer cells have membrane antigens that cross-react with fetal hepatocytes (Shi et al., 1977). To further clarify the distribution of this embryonic antigen on these cell surfaces, we performed electron microscopy using the ferritin-labeled antibody technique. The results of this experiment further confirmed the immune membrane fluorescence observed by the phenomenon, indicating that the human body