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本文对20名健康对照者和59例有上腹痛,体重减轻及(或)腹泻的患者于肠促胰液素刺激前、后以超声检查测量了胰管的直径。无胰病者在肠促胰液素刺激后显示明显的比基础管径大90%的胰管扩张,而大多数慢性胰腺炎患者中则未观察到明显的由肠促胰液素诱发的胰管扩张。具有局限性胰管狭窄的患者在刺激后有明显而持续胰管扩张。在有胰管系统畸形的患者中,经肠促胰液素刺激后未能发现一致的反应。在本研究中,超声图肠促胰液素试验显示对诊断慢性胰腺炎有92%的敏感性和95%的特异性,这些结果证实这种诊断方法可作为胰病的一个筛检试验。
In this paper, 20 healthy controls and 59 patients with upper abdominal pain, weight loss and / or diarrhea were tested for pancreatic duct diameter before and after stimulation with incretin. Patients with no pancreatic disease showed marked dilatation of the pancreatic duct 90% greater than the basal diameter upon stimulation of the incretin, whereas no significant pancreatic dilatation induced by the incretin was observed in most patients with chronic pancreatitis . Patients with localized pancreatic duct stricture experienced significant and sustained dilatation of the duct after stimulation. In patients with pancreatic duct deformities, no consistent response was found after stimulation with incretin. In this study, the sonogram of pancreatic secretions showed 92% sensitivity and 95% specificity for the diagnosis of chronic pancreatitis. These results confirm that this diagnostic method can be used as a screening test for pancreatic disease.