目的:了解F10基因在部分正常组织及肿瘤组织中的表达情况。方法:利用原位杂交和免疫组化方法对F10在部分正常组织和肿瘤组织中的mRNA和蛋白表达情况进行分析。结果:F10基因不仅在腺癌组织中表达呈阳性,在鳞癌组织中表现出较腺癌更强的强阳性,并且在正常组织中也有一定的表达。结论:F10是一个在多种组织普遍表达的细胞内蛋白,其功能可能与物质转运相关。 Objective: To understand the expression of F10 gene in some normal tissues and tumor tissues. Methods: In situ hybridization and immunohistochemistry were used to analyze the mRNA and protein expression of F10 in some normal and tumor tissues. Results: The F10 gene was not only positive in adenocarcinoma, but also stronger in adenocarcinoma than in squamous cell carcinoma, and it was also expressed in normal tissues. Conclusion: F10 is an intracellular protein that is widely expressed in many tissues and its function may be related to substance transport.