用龈上皮细胞在底物上培养，倒置显微镜下观察生长晕（ｏｕｔｇｒｏｗｔｈ）扩展的程度，扫描电镜下观察细胞贴附情况。细胞在１～８ｄ的培养中在硅酮底物上形成的生长晕明显小于在羟基磷灰石上的生长晕。电镜观察见上皮细胞直接附着ＨＡ，可见分裂相，上皮细胞不附着硅酮，少分裂相。硅酮作为生物隔膜材料（ＢＭＴ）能阻止上皮细胞生长且对牙周病治疗防止龈上皮过长有一定临床意义。 The gingival epithelial cells were cultured on the substrate, the degree of expansion of the outgrowth was observed under an inverted microscope, and the cell attachment was observed under a scanning electron microscope. The cell growth halogens formed on the silicone substrate during 1 to 8 days of culture were significantly less than those on hydroxyapatite. Electron microscopy showed epithelial cells attached directly to the HA, visible split phase, epithelial cells do not attach silicone, less split phase. Silicone as a biological membrane material (BMT) prevents epithelial cell growth and has clinical significance in the treatment of periodontal disease to prevent the excess of the gingival epithelium.