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异名 Navelbine 化学名 3′,4′-二去氢-4-去氧-8′-降长春花碱酒石酸盐药效分类抗癌药上市厂商 (法国)Pierre Fabre,1989年上市本品是一种新的半合成长春花生物碱,在长春花碱环上进行了化学修饰,将九元环变为八元环,导致了本品的适用范围和毒性与临床应用的长春碱和长春新碱等不同。药理作用本品与其它长春碱类相似,是通过干扰细胞有丝分裂期微管的聚集而产
Synonyms Navelbine Chemical name 3 ’, 4’-didehydro-4-deoxy-8’- vinblastine Tartrate Pharmacopoeia Categories Anti-cancer drugs listed manufacturers (France) Pierre Fabre, listed in 1989 This product is a The new semisynthetic vinca alkaloids, chemical modification of the vinca ring, the nine-membered ring into a eight-membered ring, resulting in the scope and toxicity of this product and clinical application of vinblastine and vincristine Different. Pharmacological effects This product is similar to other vinca alkaloids, is by interfering with the cell mitosis microtubule aggregation and production