论文部分内容阅读
目的探讨香远合剂与“云克”联合治疗131Ⅰ放射后Graves眼病的近期临床疗效。方法采用131Ⅰ放射治疗后1个月内的Graves眼病患者48例,随机分为试验组与对照组,试验组采用香远合剂配合“云克”治疗,对照组单用“云克”治疗,治疗前后4月由相同的眼科医生检查患者眼部情况,同时测定患者甲状腺激素水平。治疗4月后采用NOSPECS分类标准及眼病指数判断疗效,采用SPSS7.5统计软件进行分析。结果对于131Ⅰ放射核素治疗后患者,单独应用“云克”治疗,控制症状较慢,而试验组病例的Graves眼病体征及甲状腺激素水平改善得较多且明显。疗效与疗程的长短有关,多表现为疗程长者效果更好,无效者多为疗程不足30 d。结论香远合剂配合“云克”治疗131Ⅰ放射后Graves眼病具有较高的疗效,又克服了131Ⅰ放射治疗Graves眼病后带来的副作用,如有条件,适当延长疗程可能获得更好的疗效,具有临床应用价值和开发潜力,值得临床推广。
Objective To investigate the short-term clinical efficacy of the combination of “Xiang-Yuan” and “Yunke” in the treatment of 131I-Graves ophthalmopathy. Methods Forty-eight patients with Graves ophthalmopathy within 1 month after 131 Ⅰ radiotherapy were randomly divided into experimental group and control group. The experimental group was treated with “Xiang Yuan Mixture” with “Yun Ke” and the control group with “Yun Ke ”Treatment, before and after treatment in April by the same ophthalmologist examination of patients with eye conditions, and determination of thyroid hormone levels in patients. After treatment for 4 months, the NOSPECS classification criteria and eye disease index were used to judge the curative effect. SPSS 7.5 statistical software was used to analyze the curative effect. Results 131I radionuclide therapy patients treated with “Yunke ” alone, the control of symptoms is slow, and the test group of patients with Graves eye disease signs and thyroid hormone levels improved more and more obvious. Efficacy and the length of the course of treatment, and more performance for the treatment of elderly better, mostly ineffective treatment for less than 30 d. Conclusions Fragrant mixture with “Yunke” treatment of 131 Ⅰ radiation after Graves eye disease has a higher efficacy, but also overcome the 131 Ⅰ radiation after the side effects of Graves eye disease, if conditions, the appropriate extension of the course of treatment may be better effect , With clinical application value and development potential, it is worth clinical promotion.