玻璃体腔内注射曲安耐德治疗视网膜分支静脉阻塞引起的黄斑水肿:前导研究

来源 :世界核心医学期刊文摘.眼科学分册 | 被引量 : 0次 | 上传用户:lilanlan999
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Purpose: To evaluate treatment of macular oedema due to branch retinal vein occlusion (BRVO) with intravitreal triamcinolone acetonide. Methods: In a prospective case series, nine patients with macular oedema due to BRVO received an intravitreal injection of 4 mg triamcinolone acetonide. Examination included best-corrected visual acuity (BCVA) for distance and reading, intraocular pressure (IOP) measurement, fluorescein angiography and high resolution imaging by optical coherence tomography, preoperatively and at 1 week, 1 month, 3 and 6 months postoperatively. Results: Preoperative mean BCVAs were 1.3 ±0.8 for distance vision, and 1.1 ±0.3 for reading acuity, respectively. A significant improvement in reading acuity was observed until 1 month (0.7 ±0.4, p=0.02). No significant reduction in mean macular thickness was observed. Conclusions: Intravitreal injection of triamcinolone acetonide led to a significant improvement in mean VA in patie nts with macular oedema due to BRVO. However, the significant effect was not permanent and persisted for only 1 month. Methods: To evaluate treatment of macular odema due to branch retinal vein occlusion (BRVO) with intravitreal triamcinolone acetonide. Methods: In a prospective case series, nine patients with macular odema due to BRVO received an intravitreal injection of 4 mg triamcinolone acetonide. best-corrected visual acuity (BCVA) for distance and reading, intraocular pressure (IOP) measurement, fluorescein angiography and high resolution imaging by optical coherence tomography, preoperatively and at 1 week, 1 month, 3 and 6 months postoperatively. BCVAs were 1.3 ± 0.8 for distance vision, and 1.1 ± 0.3 for reading acuity, respectively. A significant improvement in reading acuity was observed until 1 month (0.7 ± 0.4, p = 0.02). No significant reduction in mean macular thickness was observed. Conclusions: Intravitreal injection of triamcinolone acetonide led to a significant improvement in mean VA in patients with macular odedema due to BRVO. Howev er, the significant effect was not permanent and persisted for only 1 month.
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