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目的探讨鼻塞式持续气道正压通气(CPAP)治疗儿童呼吸衰竭的疗效。方法 42例不同原因引起的呼吸衰竭患儿使用常规氧疗、鼻塞式CPAP及呼吸机进行治疗,比较治疗前后的临床情况(气喘、气促、三凹征)、动脉血气[pH、动脉血氧分压(PaO2)、动脉血二氧化碳分压(PaCO2)]的变化及住院时间、预后等。结果常规氧疗有效率为50%,CPAP有效率为79%,呼吸机有效率为100%。住院时间CPAP组为8.9 d,较常规氧疗(12.5 d)和呼吸机治疗(12.7 d)均明显缩短(P<0.05)。结论鼻塞式CPAP治疗儿童呼吸衰竭疗效显著,可以减少有创通气的应用及缩短住院时间,避免了有创呼吸支持对儿童气道的损害,具有无创伤、易操作、低费用、高疗效等优点,值得推广应用。
Objective To investigate the efficacy of nasal continuous positive airway pressure (CPAP) in children with respiratory failure. Methods A total of 42 children with respiratory failure caused by different causes were treated with routine oxygen therapy, nasal CPAP and ventilator, and the clinical conditions (asthma, shortness of breath, trigeminal tract), arterial blood gas [pH, arterial oxygen Partial pressure (PaO2), arterial carbon dioxide partial pressure (PaCO2)] changes and length of stay, prognosis and so on. Results The conventional oxygen therapy was 50% effective, CPAP effective rate was 79% and ventilator effective rate was 100%. The duration of hospitalization was 8.9 days in CPAP group, which was significantly shorter than that in routine oxygen therapy (12.5 days) and ventilator therapy (12.7 days) (P <0.05). Conclusions The therapeutic effect of nasal CPAP in children with respiratory failure is significant, which can reduce the application of invasive ventilation and shorten the length of hospital stay, and avoid the damage of invasive respiratory support to the airway of children with the advantages of non-invasiveness, easy operation, low cost and high curative effect , It is worth promoting application.