论文部分内容阅读
将人膀胱癌单克隆抗体与阿霉素偶联物,应用于载膀胱癌裸鼠导向治疗,结果表明,该偶联物以肿瘤的生长有明显的抑制作用,因而延长了供试探鼠的寿命,与对照组相比差异明显。说明偶税物中的单抗和阿霉素发挥了导向及协同杀伤靶细胞的作用,为临床应用提供了实验依据。
The human bladder cancer monoclonal antibody and doxorubicin conjugate were applied to the bladder cancer-bearing nude mice. The results showed that the conjugate had a significant inhibitory effect on the growth of the tumor, thus prolonging the life span of the test probes. Compared with the control group, the difference was significant. It shows that the monoclonal antibody and doxorubicin in the double taxation have played a role of targeting and synergistic killing of target cells, providing experimental basis for clinical application.