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临床医师遇到急性肺炎时,常应考虑过敏因素,如果以往呼吸道有类似过敏史,则提示为一种慢性过敏疾病复发;或服用过匹拉米洞、青霉素、磺胺类和金制剂等药物;症状出现前4—6小时胃一次大量吸入有机尘屑或霉菌孢子;出现红疹或剥脱性皮炎等不同皮肤反应;嗜酸性粒细胞增高约6—50%等,都高度提示为过敏性肺炎。药物的过敏反应,多因药物分子作为不全抗原而引起但与药物毒性无关,临床上出现发热,呼吸短促或咳嗽等类似肺部感染症状,但嗜酸性粒细胞常升高。X 线表现周围肺野间质水肿(间隔水肿线及血管阴影模糊)、肺泡实变或为不规则浸润及少量胸水。磺胺药物过敏的肉芽肿性血管炎还可出现
When clinicians encounter acute pneumonia, allergic factors should always be considered. If there is a history of similar allergies in the respiratory tract in the past, it suggests a relapse of chronic allergic diseases or drugs such as pirarubicin, penicillin, sulfonamides and gold preparations; Four to six hours before the onset of symptoms, a great amount of inhalation of organic dust or mold spores occurs in the stomach; different skin reactions such as rash or exfoliative dermatitis; and an increase in eosinophils of about 6-50% are highly suggestive of allergic pneumonia. Drug allergy, mostly due to drug molecules as a result of incomplete antigen and drug toxicity has nothing to do, clinically fever, shortness of breath or cough and other symptoms similar to lung infection, but often eosinophils increased. X-ray showed surrounding pulmonary interstitial edema (interval edema line and vascular shadow blur), alveolar consolidation or irregular infiltration and a small amount of pleural effusion. Sulphamethamine allergy to granulomatous vasculitis can also occur