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目的:观察芪苈强心胶囊辅助治疗慢性心力衰竭(CHF)的临床疗效。方法:选择2014年10月至2015年8月重庆医科大学附属永川中医院CHF 80例患者,随机分为两组,观察组在西医常规治疗基础上给予口服芪苈强心胶囊,对照组采用基础治疗,连续治疗3个月。观察两组患者治疗前后明尼苏达州心力衰竭生活质量问卷(MLHF)评分、6 min步行距离试验及N-末端原脑利钠肽(NT-pro BNP)的变化。结果:两组治疗后6 min步行试验距离均较前延长,MLHF评分、NT-pro BNP水平均较治疗前下降(P<0.05)。与对照组比较,观察组6 min步行距离、MLHF评分改善更明显,NT-pro BNP水平进一步下降(P<0.05)。结论:芪苈强心胶囊辅助治疗CHF临床疗效满意,能显著改善患者的生活质量。
Objective: To observe the clinical effect of Qili Qiangxin capsule in the treatment of chronic heart failure (CHF). Methods: From October 2014 to August 2015, 80 patients with CHF of Yongchuan Hospital affiliated to Chongqing Medical University were randomly divided into two groups. The observation group was given Qiliqiangxin Capsule on the basis of routine treatment of western medicine, while the control group was basal Treatment, continuous treatment for 3 months. The Minnesota Heart Failure Quality of Life Questionnaire (MLHF) score, 6-minute walk distance test and N-terminal pro-brain natriuretic peptide (NT-pro BNP) scores were observed before and after treatment in both groups. Results: The walking distance at 6 min after treatment was longer than before treatment. MLHF score and NT-pro BNP level in both groups were significantly lower than those before treatment (P <0.05). Compared with the control group, the observation group 6 min walk distance, MLHF score improved more significantly, NT-pro BNP levels decreased further (P <0.05). Conclusion: Qili Qiangxin Capsule adjuvant treatment of CHF clinical efficacy satisfactory, can significantly improve the quality of life of patients.